Archive for 01/05/2010

Abstract: The analgesic tramadol has many characteristics in common
with the antidepressant venlafaxine. The drugs are structurally
similar, share both serotonergic and noradrenergic properties, and
undergo a similar metabolic fate. In this study, a patient, who developed
significant depression following cessation of tramadol after
several years of therapy, is described. Her depression was then
treated with venlafaxine with excellent response. It appears that
tramadol may have provided a prophylactic antidepressant effect in
this patient. Because of its similarities to venlafaxine, tramadol may
possibly exert a degree of antidepressant effect in certain patients,
particularly those with chronic pain

Read more: Similar_effects_of_tramadol_and_venlafaxine_in_major_depressive_disorder

Evaluation of Opioid-Dependent Prisoners in Oral Opioid Maintenance Therapy
Dose Determination in Dual Diagnosed Heroin Addicts during Methadone Treatment

Urine Labelling Marker System for Drug Testing Improves Patient Compliance
Quality of Life as a Means of Assessing Outcome in Opioid Dependence Treatment
Why There Has Been an Excess of Overdoses in Norway Since 1990